Casco Viejo by Business Type: Which Streets Are Best for What?

FCA Group • 20 de marzo de 2026

Casco Viejo by Business Type: Which Streets Are Best for What?

Casco Viejo (also known as San Felipe or Casco Antiguo) is one of the most desirable locations in Panama City for opening a business — especially in hospitality, retail, and creative industries. But here’s what many investors and entrepreneurs don’t realize:


Not all streets in Casco Viejo perform the same.


Choosing the wrong street — even within the same neighborhood — can dramatically impact your foot traffic, visibility, and long-term success. In this guide, we break down which areas of Casco Viejo are best depending on your business type, so you can make a smarter investment.


Calle 3a & Plaza Herrera: High-End Dining and Hospitality

This is one of the most active and high-visibility zones in Casco Viejo.


Best for:

  • Restaurants
  • Rooftop bars
  • Boutique hotels
  • Upscale hospitality concepts


Why it works:

  • Constant foot traffic from tourists and locals
  • Surrounded by established restaurants and nightlife
  • Strong evening activity and visibility


This area is ideal if your business depends on ambience, visibility, and premium positioning.


Avenida Central: Retail and Tourist-Focused Businesses

Avenida Central is one of the busiest pedestrian corridors in Casco Viejo, connecting key plazas and attractions.


Best for:

  • Souvenir shops
  • Boutique retail
  • Coffee shops and grab-and-go concepts
  • Tour-related businesses


Why it works:

  • Heavy daytime foot traffic
  • High tourist exposure
  • Strong impulse-buy environment


If your business relies on volume and walk-ins, this is one of the strongest locations in Casco.


Calle 9a & Calle 10a: Nightlife and Social Concepts

These streets are known for their energy after hours, making them perfect for nightlife-driven businesses.


Best for:

  • Bars and lounges
  • Late-night food concepts
  • Music venues
  • Social dining experiences


Why it works:

  • High evening and weekend traffic
  • Younger, social crowd
  • Strong brand exposure through nightlife


This is where you want to be if your business thrives on atmosphere and social activity.


Calle San Felipe & Secondary Streets: Hidden Gems and Boutique Concepts

Some of the most successful businesses in Casco Viejo are not on the main streets — they’re tucked away in quieter areas with strong branding.


Best for:

  • Art galleries
  • Boutique studios
  • Wellness concepts (yoga, spa, etc.)
  • Creative or niche retail


Why it works:

  • Lower rent compared to prime streets
  • Unique, discovery-based customer experience
  • Opportunity to build a destination brand


These locations work best for businesses that don’t rely solely on foot traffic, but instead create their own demand.


Santa Ana: The Next Commercial Frontier

Located right next to Casco Viejo, Santa Ana is quickly becoming one of the most talked-about areas for early investors.


Best for:

  • Restaurants and cafés
  • Mixed-use developments
  • Hospitality projects
  • Long-term commercial investments


Why it works:

  • Lower entry prices than central Casco
  • Government incentives for restoration
  • Increasing development and investor interest


Santa Ana is ideal for those looking to get in early before prices rise further.


How to Choose the Right Street for Your Business

Before committing to a location in Casco Viejo, ask yourself:


  • Do I need constant foot traffic or can I build destination traffic?
  • Is my concept daytime-driven or nightlife-focused?
  • Does my brand require high visibility or exclusivity?
  • What level of renovation and permitting am I prepared for?


The answers to these questions will guide you toward the right micro-location.


Ready to Find the Right Commercial Space in Casco Viejo?

Whether you’re opening a restaurant, boutique hotel, retail shop, or creative concept, location within Casco Viejo can make or break your success.


FCA Group helps investors and business owners secure the right commercial spaces in San Felipe and surrounding areas, with guidance on location strategy, permits, and long-term value.



Browse commercial properties in Casco Viejo or Contact our team to get started.